Lichtman's Atlas Of Hematology Pdf 16 'LINK'

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Within the laboratory setting, the complete blood count is a relatively straightforward procedure, though it can be complicated by artifacts and technical mistakes. Hematology technologists must collect blood samples and process the samples, as well as count and identify various cell types.[14] The procedures for the complete blood count are standardized by the American Association of Clinical Chemistry (AACC), the Clinical and Laboratory Standards Institute (CLSI) and the British National External Quality Assessment Service (NEQAS), and each laboratory must be certified to ensure that it is properly performing these tests. A small number of laboratories are accredited under the College of American Pathologists (CAP) to perform hematology tests.[14][note 3] The accuracy of the CBC is affected by hematocrit, which in turn is affected by the plasma volume and the red blood cell count. This can complicate comparisons between patients, making it difficult to compare CBC results from different samples.[note 4] An important aspect of the procedures is the use of a lyophilized blood collection tube, which enables a stable sample of blood to be collected without requiring immediate refrigeration.[note 5] The automated hematology analyzers used in a laboratory typically perform the same procedures as the manual method, but with the additional capability of providing results on a continuous or semi-continuous basis.[note 6]

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